Nganou-Makamdop K (2025)
Publication Type: Journal article, Review article
Publication year: 2025
Book Volume: 219
Journal Issue: 1
DOI: 10.1093/cei/uxaf023
Potent inflammatory responses stemming from innate and T cell activation are initiated during acute human immunodeficiency virus infection. Suppression of the virus replication by antiretroviral therapy reduces but does not normalize immune activation. By now, it is clear that residual immune activation can persist even after years of antiretroviral therapy and associates with increased risks for co-morbidities, thereby raising interest for strategies that can resolve the residual immune activation in people with human immunodeficiency virus on antiretrovirals. This brief review reports the human studies with various drugs with anti-inflammatory properties and their effects on measures of systemic immune activation on people with human immunodeficiency virus. Along with the possible reasons for conflicting outcomes, considerations for ongoing and future approaches are outlined.
APA:
Nganou-Makamdop, K. (2025). Clinical and experimental treatment of residual immune activation in people living with HIV. Clinical and Experimental Immunology, 219(1). https://doi.org/10.1093/cei/uxaf023
MLA:
Nganou-Makamdop, Krystelle. "Clinical and experimental treatment of residual immune activation in people living with HIV." Clinical and Experimental Immunology 219.1 (2025).
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