PD Dr. Jennifer Munkert

Lehrstuhl für Pharmazeutische Biologie

A dataset for machine learning-based QSAR models establishment to screen beta-lactamase inhibitors using the FARM -BIOMOL chemical library (2025) Pitakbut T, Munkert J, Xi W, Wei Y, Fuhrmann G Journal article Utilizing machine learning-based QSAR model to overcome standalone consensus docking limitation in beta-lactamase inhibitors screening: a proof-of-concept study (2024) Pitakbut T, Munkert J, Xi W, Wei Y, Fuhrmann G Journal article Photoconverting nets affect plant growth and levels of antiviral glucoevatromonoside and total cardenolides in Digitalis mariana ssp. heywoodii (P. Silva and M. Silva) Hinz (2023) Marafeli ÉAM, Chibli LA, Rocha JPM, Assis RMAd, Pinto JEBP, Pádua RMd, Kreis W, et al. Journal article Overexpression and RNAi-mediated Knockdown of Two 3β-hydroxy-Δ5-steroid dehydrogenase Genes in Digitalis lanata Shoot Cultures Reveal Their Role in Cardenolide Biosynthesis (2023) Leykauf T, Klein J, Ernst M, Dorfner M, Ignatova A, Kreis W, Lanig H, Munkert J Journal article Effects of Lipophilicity and Structural Features on the Antiherpes Activity of Digitalis Cardenolides and Derivatives (2022) De Padua RM, Kratz JM, Munkert J, Bertol JW, Rigotto C, Schuster D, Maltarollo VG, et al. Journal article Knockout of arabidopsis thaliana vep1, encoding a prise (Progesterone 5β-reductase/iridoid synthase-like enzyme), leads to metabolic changes in response to exogenous methyl vinyl ketone (mvk) (2022) Klein J, Ernst M, Christmann A, Tropper M, Leykauf T, Kreis W, Munkert J Journal article Identifying structural features for changing substrate preferences in two Plantago PRISEs (pro-gesterone 5 beta-reductase and / or iridoid synthase) (2021) Dorfner M, Klein J, Lanig H, Kreis W, Munkert J Conference contribution Overexpression of 3 beta-hydroxysteroid dehydrogenases in Digitalis lanata shoot cultures (2021) Leykauf T, Klein J, Lodel M, Kreis W, Munkert J Conference contribution Restoring cardenolide accumulation in RNAi-mediated DlP5 beta R1 and DlP5 beta R2 knockdown shoot culture lines of Digitalis lanata and studying the effects of precursor feeding on cardenolide free dark-cultured D. lanata shoots (2021) Ignatova A, Klein J, Leykauf T, Kreis W, Munkert J Conference contribution 21-Hydroxypregnane 21-O-malonylation, a crucial step in cardenolide biosynthesis, can be achieved by substrate-promiscuous BAHD-type phenolic glucoside malonyltransferases from Arabidopsis thaliana and homolog proteins from Digitalis lanata (2021) Tropper M, Höhn S, Wolf LS, Fritsch J, Kastner-Detter N, Rieck C, Munkert J, et al. Journal article, Original article